A gynogenetic screen to isolate naturally occurring recessive mutations in Xenopus tropicalis
نویسندگان
چکیده
منابع مشابه
A gynogenetic screen to isolate naturally occurring recessive mutations in Xenopus tropicalis
In the rapidly developing, diploid amphibian Xenopus tropicalis, genetics can be married to the already powerful tools of the amphibian system to overcome a disability that has hampered Xenopus laevis as a model organism: the difficulties inherent in conducting genetic analyses in a tetraploid organism with a longer generation time. We describe here a gynogenetic screen to uncover naturally occ...
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Single-point mutation in genome, for example, single-nucleotide polymorphism (SNP) or rare genetic mutation, is the change of a single nucleotide for another in the genome sequence. Some of them will produce an amino acid substitution in the corresponding protein sequence (missense mutations); others will not. This paper focuses on genetic mutations resulting in a change in the amino acid seque...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2005
ISSN: 0925-4773
DOI: 10.1016/j.mod.2004.11.001